Customized Genomics Solutions
GRO-Seq/BRIC-Seq/Bru-Seq/BruChase-Seq maps the binding sites of transcriptionally active RNA polymerase II (RNAPII). In this method, active RNAPII is allowed to run on in the presence of 5-bromouridine 5'-triphosphate (Br-UTP). RNAs are hydrolyzed and purified using beads coated with antibodies to 5-bromo-2-deoxyuridine (BrdU). The eluted RNA is deep sequenced to identify RNAs that are actively transcribed by RNAPII.
We at National Genomics Core-CDFD have meticulous quality control in each step of the sequencing project. Experts with PhD and International experience are using top-notch technologies to carefully plan and generate high quality, meaningful data.
De novo sequencing is sequencing a novel genome where there is no reference sequence available for alignment. It is used to generate accurate reference sequences, even for complex or polyploid genomes and to Identify structural variants and complex rearrangements, such as deletions, inversions, or translocations.
We at National Genomics Core-CDFD have meticulous quality control in each step of the sequencing project. Experts with PhD and International experience are using top-notch technologies to carefully plan and generate high quality, meaningful data.
